The alleged incident happened when two men became involved in an argument.
Police understand of the men, a 24-year-old man allegedly smashed the other man over the head with a broken beer bottle.
As a result, a 25-year-old man sustained a severe laceration to the head and lost consciousness.
A 24-year-old man also sustained a slash injury to his shoulder and a minor head injury.
Both men have been conveyed to hospital, the 25-year-old man in a serious condition while the younger man’s injuries are not considered to be life-threatening.
Darebin CIU detectives are investigating the stabbing.