Police are urgently appealing for assistance to locate missing Bundoora woman Moira Coulson.
The 45-year-old was last seen in Lawrence Court, Bundoora about 2am on 25 September.
Moira is known to frequent the Melbourne CBD and Frankston areas and travels on buses and trains.
She is described as 162cm tall, with a solid build, blonde shoulder-length hair and thick-rimmed glasses.
Police have concerns for her welfare due to a medical condition.
Anyone who sights Moira or has information is urged to contact Mill Park Police Station on (03) 9407 3333.