It is alleged the stolen Subaru with four occupants onboard was travelling on the Eastern Freeway in North Balwyn when it struck a barrier at the Bulleen Road exit about 10:55pm on 2 September.
The crash caused the Eastern Freeway city-bound to be closed for several hours.
The 20-year-old female driver, and her three passengers, a 21-year-old Seaford man, an 18-year-old Springvale South man and a 19-year-old man from Noble Park, were all taken to hospital following the crash.
MCIU detectives have charged the Caulfield woman with dangerous driving causing serious injury. She has been bailed to appear at Melbourne Magistrates’ Court next Monday, 14 September.