Police understand the truck was travelling on Princes Street when the driver appears to have lost control coming out of a bend just after midnight.
The truck travelled over a centre median strip, collected traffic lights and continued on into the service station.
It then struck a car at the petrol bowsers before coming to a stop just outside the shopfront.
Luckily no one was seriously injured with the motorist who had just filled up their car in the shop at the time.
The driver of the truck, who is believed to be aged in his 40s, was taken to hospital with non-life-threatening injuries.
The main road through Traralgon was closed for some time with westbound traffic on Princess Street completely blocked.
Eastbound traffic on Princes Street was down to one lane.
Heavy haulage operators were on-site during the night to assist in clearing the scene.